2D Molybdenum Sulfide-Based Materials for Photo-Excited Antibacterial Application

Adv Healthc Mater. 2022 Jul;11(13):e2200360. doi: 10.1002/adhm.202200360. Epub 2022 Apr 13.

Abstract

Bacterial infections have seriously threatened human health and the abuse of natural or artificial antibiotics leads to bacterial resistance, so development of a new generation of antibacterial agents and treatment methods is urgent. 2D molybdenum sulfide (MoS2 ) has good biocompatibility, high specific surface area to facilitate surface modification and drug loading, adjustable energy bandgap, and high near-infrared photothermal conversion efficiency (PCE), so it is often used for antibacterial application through its photothermal or photodynamic effects. This review comprehensively summarizes and discusses the fabrication processes, structural characteristics, antibacterial performance, and the corresponding mechanisms of MoS2 -based materials as well as their representative antibacterial applications. In addition, the outlooks on the remaining challenges that should be addressed in the field of MoS2 are also proposed.

Keywords: 2D materials; antibacterial; drug-resistance bacteria; molybdenum sulfide; phototherapy.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology
  • Disulfides / chemistry
  • Disulfides / pharmacology
  • Escherichia coli*
  • Humans
  • Molybdenum* / chemistry
  • Molybdenum* / pharmacology
  • Phototherapy

Substances

  • Anti-Bacterial Agents
  • Disulfides
  • Molybdenum
  • molybdenum disulfide