Systematic review and meta-analysis of the therapeutic management of patients with cervicogenic dizziness

J Man Manip Ther. 2022 Oct;30(5):273-283. doi: 10.1080/10669817.2022.2033044. Epub 2022 Apr 6.

Abstract

Background: Patients with cervicogenic dizziness (CGD) present with dizziness, cervical spine dysfunctions, and postural imbalance, symptoms that can significantly impact their daily functioning.

Objectives: To provide evidence-based recommendations for the management of patients with CGD.

Methods: Three databases were searched for randomized controlled trials (RCTs) (last search 15 May 2021). Outcome measures included dizziness, cervical spine, and balance parameters. Cochrane standard methodological procedures were used and included the RoB 2.0 and GRADE. Where possible, RCTs were pooled for meta-analysis.

Results: Thirteen RCTs (n = 898 patients) of high (two RCTs), moderate (five RCTs), and low (six RCTs) methodological quality were analyzed. Six RCTs were included in the meta-analysis. Only three RCTs specified the cause of CGD. They showed inconsistent findings for the effectiveness of exercise therapy in patients with traumatic CGD. Manual therapy and manual therapy combined with exercise therapy may reduce CGD, cervical spine, and balance dysfunctions.

Conclusion: There is moderate quality of evidence that manual therapy reduces CGD, cervical spine, and balance symptoms. When manual therapy is combined with exercise therapy, the positive effect on CGD, cervical spine, and balance symptoms is even stronger. However, the quality of the evidence here is very low.

Keywords: Dizziness; cervical vertebrae; exercise therapy; musculoskeletal manipulations.

Publication types

  • Meta-Analysis
  • Systematic Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cervical Vertebrae
  • Dizziness* / diagnosis
  • Dizziness* / etiology
  • Dizziness* / therapy
  • Exercise Therapy
  • Humans
  • Musculoskeletal Manipulations* / methods
  • Vertigo / complications

Grants and funding

This work was supported by the University of Antwerp (Faculty of Medicine and Health Sciences), Wilrijk 2610, Antwerp, Belgium;