Use of Sugar Cane Bagasse as Solid Extraction Phase Sorbent to Analyze Hormones from Industrial Effluent

Daniel T Lebre; Velaphi C Thipe; Marycel E B Cotrim; José Oscar V Bustillos

doi:10.1021/acsomega.1c06064

Use of Sugar Cane Bagasse as Solid Extraction Phase Sorbent to Analyze Hormones from Industrial Effluent

ACS Omega. 2022 Mar 14;7(12):10069-10076. doi: 10.1021/acsomega.1c06064. eCollection 2022 Mar 29.

Authors

Daniel T Lebre¹, Velaphi C Thipe^{1

2}, Marycel E B Cotrim¹, José Oscar V Bustillos¹

Affiliations

¹ Center of Chemistry and Environmental (CQMA), Nuclear and Energy Research Institute (IPEN), Avenida Prof. Lineu Prestes 2242, Cidade Universitária, São Paulo, São Paulo 05508-000, Brazil.
² Department of Radiology, Institute of Green Nanotechnology, School of Medicine, University of Missouri, Columbia, Missouri 65212, United States.

Abstract

Sugar cane bagasse (SCB) is an abundant byproduct of sugar and bioethanol mills. It has been effectively used as a low-cost biosorbent to remove hazardous chemical compounds from a variety of effluent sources. Herein, we report on the preparation of SCB and its use as a solid phase extraction (SPE) sorbent to retain synthetic hormones (ethinylestradiol, drospirenone, and levonorgestrel) from industrial pharmaceutical plant effluent samples prior to LC-MS/MS quantitative analysis. We evaluated the reproducibility and recoveries and accuracy data analyses were compared with that of commercial SPE (cSPE) cartridges. The results from the evaluated parameters indicated that the SCB bed had an efficiency of >99%, comparable to that of cSPE cartridges, demonstrating the applicability and feasibility of this material as an effective and green chemistry alternative, as well as its biosorbent potential to remove hormones from industrial pharmaceutical effluent.