Early strong predictors of decline in instrumental activities of daily living in community-dwelling older Japanese people

PLoS One. 2022 Apr 5;17(4):e0266614. doi: 10.1371/journal.pone.0266614. eCollection 2022.

Abstract

Objective: Our aim is to determine the strong predictors of the onset of instrumental activities of daily living (IADL) decline in community-dwelling older people.

Design: A prospective cohort study with a two-year follow-up.

Setting: Kashiwa City, Chiba Prefecture, Japan and Toshima Ward, Tokyo Metropolitan, Japan.

Participants: The data were acquired from two cohorts. The final sample comprised 1,523 community-dwelling older people aged 65-94 years (681 men, 842 women). They were individuals who were independent in IADL at baseline and participated in follow-up IADL assessments two years later.

Measurements: At baseline, comprehensive assessments were performed including: health interview, gait function, hand-grip strength, skeletal muscle mass, balance function, oral function, dietary lifestyle, cognitive function, quality of life, mental status, and social network. When the two-year follow-up was performed, IADL declines were observed in 53 out of 1,523 people. The association of each Z-transformed parameter with the occurrence of IADL decline was examined by employing a binominal logistic regression model adjusting for age, gender, body weight, body height, and medical history. An odds ratio (OR) and a 95% confidence interval were calculated and compared between different parameters.

Results: A decrease in walking speed and one-legged stance time, whereas an increased timed up & go test time was associated with significant ORs for the occurrence of IADL decline.

Conclusion: Gait-related parameters appear to be the strong predictors of the onset of IADL decline in community-dwelling older people.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Activities of Daily Living* / psychology
  • Aged
  • Female
  • Humans
  • Independent Living* / psychology
  • Japan / epidemiology
  • Male
  • Prospective Studies
  • Quality of Life

Grants and funding

The project via which data were collected was supported by Health and Labor Sciences Research Grants (H24-Choju-Ippan-002, H25-Choju-Ippan-005) from the Ministry of Health, Labour and Welfare of Japan, 2014 Health and Labour Sciences Research Grants (H26-Choju-Itaku) from the Ministry of Health, Labour and Welfare of Japan, 2015-2016 the Research and Development Grants for Longevity Science from the Japan Agency for Medical Research and Development (15dk0107013h0002, 16dk0110013h0003). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.