History of Otolaryngology: Globus Pharyngeus as "Globus Hystericus"

Otolaryngol Head Neck Surg. 2023 Apr;168(4):889-892. doi: 10.1177/01945998221093517. Epub 2023 Feb 5.

Abstract

Globus pharyngeus is the uncomfortable sensation of a "lump in the throat," and at present it has many recognized pathophysiologic causes. However, until relatively recently, this condition was often labeled "globus hystericus" and was thought to be a manifestation of hysteria or anxiety. In this commentary, we briefly review the history surrounding the initial treatment of globus pharyngeus sensation as a hysterical condition rooted in anxiety/psychological causes; then, we briefly review the emerging evidence that roots globus pharyngeus sensation within a constellation of pathophysiologies that are related to pharyngoesophageal inflammation and irritation rather than psychological disorders.

Keywords: globus; head neck surgery; history; hystericus; laryngeal; laryngopharyngeal; larynx; lump; otolaryngology; reflux; throat; voice.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anxiety
  • Globus Sensation
  • Humans
  • Inflammation
  • Neck
  • Otolaryngology*
  • Pharynx*