Axillary masses as clinical manifestations of male sweat gland carcinoma associated with extramammary Paget's disease and accessory breast carcinoma: two cases report and literature review

World J Surg Oncol. 2022 Apr 4;20(1):109. doi: 10.1186/s12957-022-02570-w.

Abstract

Background: Male cases of accessory breast carcinoma and sweat gland carcinoma associated with extramammary Paget's disease of the axilla are uncommon. In clinical diagnosis and treatment, it is necessary to determine the disease carefully and make a reasonable treatment strategy according to the patient's situation.

Case presentation: We described two male cases of the special tumor with an axillary mass as the first clinical symptom, one of which was diagnosed as accessory breast cancer and the other as sweat gland cancer associated with extramammary Paget's disease. We treated the two diseases individually in the hopes of providing a reference for the diagnosis and management of diseases with axillary nodules as the initial symptom.

Conclusions: The reports of these two cases can provide reference and corresponding thinking for clinical differentiation of axillary lymphadenopathy caused by different causes and subsequent treatment. These two cases may further enrich the database of rare cases and provide some ideas for the treatment of axillary lymphadenopathy caused by different causes.

Keywords: Accessory breast carcinoma; Axillary mass; Extramammary Paget’s disease; Sweat gland carcinoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Axilla / pathology
  • Breast Neoplasms* / pathology
  • Humans
  • Male
  • Paget Disease, Extramammary* / diagnosis
  • Paget Disease, Extramammary* / surgery
  • Sweat Gland Neoplasms* / surgery
  • Sweat Glands / pathology