Real-time assessment of tissue oxygen saturation during endovascular therapy for chronic limb threatening ischemia using a novel oximeter

Naoki Unno; Kazunori Inuzuka; Masaki Sano; Masatsugu Niwayama; Ena Naruse; Hiroya Takeuchi

doi:10.1016/j.jvscit.2021.07.001

Real-time assessment of tissue oxygen saturation during endovascular therapy for chronic limb threatening ischemia using a novel oximeter

J Vasc Surg Cases Innov Tech. 2021 Jul 22;8(2):158-163. doi: 10.1016/j.jvscit.2021.07.001. eCollection 2022 Jun.

Authors

Naoki Unno^{1

2

3}, Kazunori Inuzuka^{1

2}, Masaki Sano^{1

2}, Masatsugu Niwayama⁴, Ena Naruse^{1

2}, Hiroya Takeuchi²

Affiliations

¹ Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
² Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
³ Division of Vascular Surgery, Hamamatsu Medical Center, Hamamatsu, Japan.
⁴ Department of Electrical and Electronic Engineering, Shizuoka University, Hamamatsu, Japan.

Abstract

In the present study, we have introduced a novel real-time, near-infrared spectroscopy oximeter, the TOE-20 (Astem, Co, Ltd, Kawasaki, Japan), which can simultaneously measure the regional tissue oxygen saturation (rSO₂) in the skin and subcutaneous tissue at three angiosomes of the foot. Seven patients with chronic limb threatening ischemia who had undergone successful revascularization of the superficial femoral artery were included. The analysis revealed a significant correlation between the rSO₂ and skin perfusion pressure. After revascularization, the rSO₂ and skin perfusion pressure had both increased at the three regions, although the increase at the plantar foot was insignificant. These results indicate that the TOE-20 can be successfully used to monitor the rSO₂ during endovascular treatment.

Keywords: Chronic limb-threatening ischemia; Endovascular treatment; Foot ulcer; Near-infrared spectroscopic oximeter; Regional oxygen saturation monitoring.