Psoriasis Flare-Up After COVAXIN BBV152 Whole Virion Inactivated Vaccine

Dj L Infimate; Deepak Yumnam; Santosh S Galagali; Ankita Kabi; Nidhi Kaeley

doi:10.7759/cureus.22311

Psoriasis Flare-Up After COVAXIN BBV152 Whole Virion Inactivated Vaccine

Cureus. 2022 Feb 17;14(2):e22311. doi: 10.7759/cureus.22311. eCollection 2022 Feb.

Authors

Dj L Infimate¹, Deepak Yumnam², Santosh S Galagali¹, Ankita Kabi³, Nidhi Kaeley¹

Affiliations

¹ Emergency Medicine, All India Institute of Medical Sciences, Rishikesh, IND.
² Dermatology, All India Institute of Medical Sciences, Rishikesh, IND.
³ Emergency Medicine (Anesthesiology), All India Institute of Medical Sciences, Rishikesh, IND.

Abstract

Psoriasis is an inflammatory skin condition with a chronic relapsing course that can negatively impact a patient's quality of life. Various triggering factors can cause the flare-up of psoriasis, which also include vaccination. The most common vaccine associated with this is influenza. In this global pandemic of coronavirus disease 2019 (COVID-19), emergency authorization for mass vaccination has been adopted by many countries in the world. Psoriasis flare has been reported after the Pfizer COVID-19 vaccine and CoronaVac vaccine. Currently, both the virus-causing disease and the vaccines are still being studied owing to their dynamicity. We report a case of a 21-year-old gentleman with chronic plaque psoriasis of three years, who developed generalized pustular psoriasis eruption after administration of the first dose of COVAXIN. To the currently available literature, this was the first case of this complication associated with COVAXIN.

Keywords: covid; flare-up; psoriasis; trigger; vaccine.

Publication types

Case Reports