Recent insights into vitamin D, adipocyte, and adipose tissue biology

Obes Rev. 2022 Aug;23(8):e13453. doi: 10.1111/obr.13453. Epub 2022 Apr 2.

Abstract

Several studies bring strong evidence for an active role of vitamin D and its metabolites in physiological adipocyte and adipose tissue processes in adulthood. This role includes effects of vitamin D on key adipose tissue and adipocyte biology parameters, including adipogenesis, energy metabolism, and inflammation. Interestingly, recent data also point to a role of maternal vitamin D deficiency in adipocyte and adipose tissue metabolic programming in offspring. This review summarizes the current state of knowledge on the biological effect of vitamin D on adipocyte/adipose tissue physiology.

Keywords: maternal programming; micronutrients; obesity; preventive nutrition.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipocytes / metabolism
  • Adipogenesis
  • Adipose Tissue / metabolism
  • Adult
  • Biology
  • Humans
  • Vitamin D Deficiency* / complications
  • Vitamin D*

Substances

  • Vitamin D