Hospital Variation and Associated Organizational Factors of Pregnancy-Related Venous Thromboembolism in China

Clin Appl Thromb Hemost. 2022 Jan-Dec:28:10760296221076148. doi: 10.1177/10760296221076148.

Abstract

Objective: Identifying organizational factors affecting venous thromboembolism (VTE) incidence and variations between hospitals.

Methods: From a 2019 survey of VTE and live births in 113 hospitals, organizational factors: (hospital type, characteristics, live birth number), resource availability: (D-dimer, B-scan ultrasonography of lower extremity veins, computed tomographic pulmonary angiography [CTPA], and competency: [risk assessment, use of anticoagulants and patient education], data were collected and the associations, weighted by live birth number, analyzed.

Results: Of 113 hospitals in China, 770,828 live births and 526 cases of VTE (68.2 per 100,000 live births) were reported. Nine hospitals lacked B-scan ultrasonography of lower extremity veins and 22 lacked CTPA. Prevalence rates of VTE rates were higher in general hospitals (Odds ratio [OR] = 4.251, 95% CI: 3.373-5.357), hospitals with live births < 10,000 (OR = 1.650-2.193), and hospitals without B-scan ultrasonography (OR = 1.661, 95% CI: 1.096-2.518). Hospitals implementing patient education, had a lower risk of VTE (OR = 0.296-0.374), and VTE rate decreased with the annual increase in live births.

Conclusions: Improved hospital resource availability and competency, especially patient education, is vital for reducing VTE-related maternal mortality and morbidity risk.

Keywords: China; hospital; pregnancy; vein thromboembolism.

MeSH terms

  • Anticoagulants
  • Female
  • Hospitals
  • Humans
  • Pregnancy
  • Risk Assessment
  • Ultrasonography / methods
  • Venous Thromboembolism* / epidemiology

Substances

  • Anticoagulants