Predicting HPV vaccination among Tdap vaccinated adolescents in Georgia at the county level

Ann Epidemiol. 2022 Jun:70:74-78. doi: 10.1016/j.annepidem.2022.03.008. Epub 2022 Mar 28.

Abstract

Purpose: Vaccinations are reported at the state level, but services are delivered at the county level through health departments (HD). This research contributes statistical models to predict county level HPV vaccination.

Methods: Using a cross sectional study design, secondary data were analyzed for the years 2016-2018 for all counties of GA. Study population was male and female adolescents aged 13-17 who received the tetanus, diphtheria and pertussis (Tdap) vaccine. The number of administered HPV vaccine doses and HPV vaccination coverage rate were modeled using indicators of HD clinic access, age, sex, race/ethnicity, socioeconomic status, education, median household income, health insurance, and urban/rural residence.

Results: By county the number of administered HPV vaccine doses showed a statistically significant positive association with indicators of HD clinic access: public transit and the number of HD private clinics. HPV vaccination coverage showed a statistically significant negative association with White race and rural residency.

Conclusion: Examining Tdap vaccinated adolescents conservatively predicted HPV vaccination and controlled for multiple confounders such as vaccination ineligibility, vaccine exemption, and vaccine opposition. Within this population, public health professionals and clinicians could use these statistical models to target HPV vaccination efforts among non-Hispanic whites and rural communities at the county level.

Keywords: Adolescent; Diphtheria-Tetanus-Pertussis vaccine; Human Papillomavirus vaccine; Small area analysis; Vaccines.

MeSH terms

  • Adolescent
  • Cross-Sectional Studies
  • Diphtheria*
  • Female
  • Georgia
  • Humans
  • Male
  • Papillomavirus Infections* / prevention & control
  • Papillomavirus Vaccines* / therapeutic use
  • Tetanus*
  • Vaccination
  • Whooping Cough* / prevention & control

Substances

  • Papillomavirus Vaccines