Managing Pain and Discomfort in Children with Cancer

Curr Oncol Rep. 2022 Aug;24(8):961-973. doi: 10.1007/s11912-022-01277-1. Epub 2022 Mar 30.

Abstract

Purpose of review: Approximately 15,600 children are diagnosed with cancer annually. Many of these children have cancer-related pain that improves with cancer treatment, but some develop intractable pain from cancer progression or sequelae from treatment modalities. The purpose of this paper is to provide a critical evaluation of the literature relevant to pain management in children with cancer. We intend to emphasize important and up-to-date findings in pharmacology, interventional pain management, and complementary and alternative medicine.

Recent findings: Alternative medications and routes of administration, complementary and alternative medicine techniques, and interventional pain procedures offer possible routes for a multi-pronged pediatric cancer pain management plan, although high-level data is often lacking. To improve pediatric cancer pain management, a multifaceted approach embracing the biopsychosocial model of pain is recommended, incorporating evidence-based pharmacology, complementary and alternative medicine techniques, and if needed, interventional pain procedures.

Keywords: Complementary and alternative medicine; Interventional pain therapy; Pediatric cancer pain.

Publication types

  • Review

MeSH terms

  • Child
  • Chronic Pain*
  • Complementary Therapies*
  • Humans
  • Neoplasms* / complications
  • Neoplasms* / therapy
  • Pain / etiology
  • Pain Management / methods