Mild venom-induced consumption coagulopathy associated with thrombotic microangiopathy following a juvenile Russell's viper (Daboia russelii) envenoming: A case report

Toxicon. 2022 Jun:212:8-10. doi: 10.1016/j.toxicon.2022.03.014. Epub 2022 Mar 26.

Abstract

Russell's viper envenoming causes venom-induced consumption coagulopathy (VICC) within hours of a bite, which is associated with thrombotic microangiopathy (TMA) and acute kidney injury (AKI) in a proportion of cases. We report a juvenile Russell's viper bite in which a patient developed mild VICC after the usual 24-h observation period, which was subsequently associated with severe AKI due to TMA. This shows the clinical importance of detecting and treating mild VICC, which may be delayed or not detected with bedside clotting tests.

Keywords: Acute kidney injury; Delayed; Russell's viper; Thrombotic microangiopathy; Venom-induced consumption coagulopathy.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury* / chemically induced
  • Animals
  • Blood Coagulation Disorders* / etiology
  • Daboia*
  • Disseminated Intravascular Coagulation* / chemically induced
  • Female
  • Humans
  • Male
  • Snake Bites* / drug therapy
  • Thrombotic Microangiopathies* / chemically induced
  • Thrombotic Microangiopathies* / complications
  • Viper Venoms / toxicity

Substances

  • Viper Venoms