A unified technique for entropy enhancement based diabetic retinopathy detection using hybrid neural network

Comput Biol Med. 2022 Jun:145:105424. doi: 10.1016/j.compbiomed.2022.105424. Epub 2022 Mar 22.

Abstract

In this paper, a unified technique for entropy enhancement-based diabetic retinopathy detection using a hybrid neural network is proposed for diagnosing diabetic retinopathy. Medical images play crucial roles in the diagnosis, but two images representing two different stages of a disease look alike. It, consequently, make the process of diagnosis extraneous and error-prone. Therefore, in this paper, a technique is proposed to address these issues. Firstly, a novel entropy enhancement technique is devised exploiting the discrete wavelet transforms to improve the visibility of the medical images by making the subtle features more prominent. Later, we designed a computationally efficient hybrid neural network that efficiently classifies diabetic retinopathy images. To examine the effectiveness of our technique, we have chosen three datasets: Ultra-Wide Filed (UWF) dataset, Asia Pacific Tele Ophthalmology Society (APTOS) dataset, and MESSIDOR-2 dataset. In the end, we performed extensive experiments to validate the performance of our technique. In addition, the comparison of the proposed scheme - in terms of accuracy, specificity, sensitivity, precision and recall curve, and area under the curve - with some of the best contemporary schemes shows the significant improvement of our techniques in terms of diabetic retinopathy classification.

Keywords: Classification; Diabetic retinopathy; Discrete wavelet transform; Histogram; Medical data; Neural network.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Diabetes Mellitus*
  • Diabetic Retinopathy* / diagnostic imaging
  • Entropy
  • Humans
  • Neural Networks, Computer
  • Wavelet Analysis