Evaluation of MXene as an adsorbent in dispersive solid phase extraction of several pesticides from fresh fruit juices prior to their determination by HPLC-MS/MS

Elnaz Marzi Khosrowshahi; Masoumeh Ghalkhani; Mohammad Reza Afshar Mogaddam; Mir Ali Farajzadeh; Esmail Sohouli; Mahboob Nemati

doi:10.1016/j.foodchem.2022.132773

Evaluation of MXene as an adsorbent in dispersive solid phase extraction of several pesticides from fresh fruit juices prior to their determination by HPLC-MS/MS

Food Chem. 2022 Aug 30:386:132773. doi: 10.1016/j.foodchem.2022.132773. Epub 2022 Mar 23.

Authors

Elnaz Marzi Khosrowshahi¹, Masoumeh Ghalkhani², Mohammad Reza Afshar Mogaddam³, Mir Ali Farajzadeh⁴, Esmail Sohouli⁵, Mahboob Nemati⁶

Affiliations

¹ Food and Drug Safety Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
² Electrochemical Sensors Research Laboratory, Department of Chemistry, Faculty of Science, Shahid Rajaee Teacher Training University, Lavizan, P.O. Box 1678815811, Tehran, Iran.
³ Food and Drug Safety Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Pharmaceutical Analysis Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: mr.afsharmogaddam@yahoo.com.
⁴ Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, Iran; Engineering Faculty, Near East University, 99138 Nicosia, North Cyprus, Mersin 10, Turkey.
⁵ Pharmaceutical Analysis Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
⁶ Food and Drug Safety Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Pharmaceutical and Food Control, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: mr.afshar1986@gmail.com.

PMID: 35344730
DOI: 10.1016/j.foodchem.2022.132773

Abstract

This study aimed to introduce a dispersive solid phase extraction method based on MXene nanoparticles as a novel sorbent for the simultaneous extraction and determination of twelve pesticides from fresh fruit juices. In the following, a high performance liquid chromatography-tandem mass spectrometry was used for their determination in the samples. In this method, two-dimensional nanomaterials of Ti₂AlC were exfoliated in an acidic solution and then they were added into the sample solution. To enhance the sample solution and sorbent contact area, the mixture was vortexed for a few minutes. Then the adsorbed analytes onto the sorbent were eluted using acetone and then analyzed. Under optimal conditions, the calibration curves of the method were linear within the range of 3.0-1000 µg L^-1. The limits of detection, intra- and inter-day relative standard deviations, and extraction recoveries were in the ranges of 0.08-1.0 µg L^-1, 2.5-4.2%, 2.5-5.5%, and 69-75%, respectively. Performing the method verified the presence of some of the analytes in several samples. This method can help to monitor pesticides in juice samples as well as to improve our understanding the safety of foods.

Keywords: Dispersive solid phase extraction; Fruit juice; High performance liquid chromatography-tandem mass spectrometry; MXene; Pesticide.

MeSH terms

Chromatography, High Pressure Liquid
Fruit and Vegetable Juices / analysis
Liquid Phase Microextraction* / methods
Pesticides* / analysis
Solid Phase Extraction / methods
Solvents / chemistry
Tandem Mass Spectrometry

Substances

Pesticides
Solvents