Topologically-Interlocked Minicircles as Probes of DNA Topology and DNA-Protein Interactions

Arivazhagan Rajendran; Kirankumar Krishnamurthy; Seojeong Park; Eiji Nakata; Youngjoo Kwon; Takashi Morii

doi:10.1002/chem.202200839

Topologically-Interlocked Minicircles as Probes of DNA Topology and DNA-Protein Interactions

Chemistry. 2022 Apr 19;28(22):e202200839. doi: 10.1002/chem.202200839. Epub 2022 Mar 28.

Authors

Arivazhagan Rajendran¹, Kirankumar Krishnamurthy¹, Seojeong Park², Eiji Nakata¹, Youngjoo Kwon², Takashi Morii¹

Affiliations

¹ Institute of Advanced Energy, Kyoto University, Uji, Kyoto, 611-0011, Japan.
² College of Pharmacy, Ewha Womans University, Seoul, 120-750, Republic of Korea.

PMID: 35344240
DOI: 10.1002/chem.202200839

Abstract

Invited for the cover of this issue are Prof. Takashi Morii and co-workers at Kyoto University and Ewha Womans University. The cover image depicts the graphical design and atomic force microscopic (AFM) images of the synthesized topologically-interlocked DNA catenane and rotaxanes inside a frame-shaped DNA origami. Read the full text of the article at 10.1002/chem.202200108.

MeSH terms

DNA*
Humans
Microscopy, Atomic Force
Rotaxanes*

Substances

Rotaxanes
DNA