CRISPR/Cas9-Based Functional Genomics in Human Induced Pluripotent Stem Cell-Derived Models: Can "the Stars Align" for Neurodegenerative Diseases?

Mov Disord. 2022 May;37(5):886-890. doi: 10.1002/mds.28998. Epub 2022 Mar 26.

Authors

Yu Chen¹, Tiffany Ting-Yu Jong¹, Chase Chen¹, Ellen Sidransky¹

Affiliation

¹ Medical Genetics Branch, National Institutes of Health, National Human Genome Research Institute, Bethesda ,Maryland /Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.

PMID: 35338523
DOI: 10.1002/mds.28998

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Research Support, N.I.H., Intramural

MeSH terms

CRISPR-Cas Systems / genetics
Gene Editing
Genomics
Humans
Induced Pluripotent Stem Cells*
Neurodegenerative Diseases* / genetics