Aquaculture sustainable development is necessary since it is categorized as the most important source of aquatic products for human consumption and it is expected to keep growing shortly. For this reason, the addition of natural immunostimulants to fish diet to improve fish health and to preserve the environment have great importance in aquaculture. In this sense, new biotechnological tools as nature-identical compounds are now being used as feed additives to strengthen and stimulate the fish immune system to prevent and/or control diseases due to their lesser cost and higher availability than plant compounds. This review aims to present the most recent studies in which nature-identical compounds have been used in the fish diet to establish their possible use in aquaculture. Nature-identical compounds can be considered a promising alternative to be added to fish diets to promote growth performance, manipulate the gut microbiota, and improve the immune and oxidative status of fish as wells as control bacterial infections in this important aquatic industry.
Keywords: Additives; Aquaculture; Feed; Fish; Nature-identical compounds.
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