Effect of Partial vs Full Disclosure of Potential Assignment to Placebo on Participant Blinding, Perceptions of Group Assignment, and Trial Outcomes: A Randomized Clinical Trial

Jiyoon Won; Heejung Bang; Hyangsook Lee

doi:10.1001/jamanetworkopen.2022.4050

Effect of Partial vs Full Disclosure of Potential Assignment to Placebo on Participant Blinding, Perceptions of Group Assignment, and Trial Outcomes: A Randomized Clinical Trial

JAMA Netw Open. 2022 Mar 1;5(3):e224050. doi: 10.1001/jamanetworkopen.2022.4050.

Authors

Jiyoon Won¹, Heejung Bang², Hyangsook Lee¹

Affiliations

¹ Department of Science in Korean Medicine, College of Korean Medicine, Graduate School, Kyung Hee University, Seoul.
² Division of Biostatistics, Department of Public Health Sciences, University of California, Davis.

Abstract

This randomized clinical trial investigates the effect of partial vs full disclosure of potential assignment to placebo on participant blinding, perceptions of group assignment, and clinical outcomes.

Publication types

Randomized Controlled Trial
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Disclosure*
Double-Blind Method
Humans
Treatment Outcome

Grants and funding

UL1 TR001860/TR/NCATS NIH HHS/United States