We observed multisystem inflammatory syndrome in 2 older adults in the United States who had received mRNA coronavirus disease vaccine soon after natural infection. We identified 5 similar cases from the Vaccine Adverse Events Reporting System. The timing of vaccination soon after natural infection might have an adverse effect on the occurrence of vaccine-related systemic inflammatory disorders.
Keywords: COVID-19; MIS-A; SARS-CoV-2; United States; coronavirus disease; mRNA vaccine; multisystem inflammatory syndrome in adults; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.