Treatment Management of Diabetic Wounds Utilizing Herbalism: An Overview

Curr Diabetes Rev. 2023;19(1):e180322202355. doi: 10.2174/1573399818666220318095320.

Abstract

Background and objectives: Diabetes Mellitus, commonly known as DM, is a metabolic disorder which is characterized by high blood glucose level, i.e., chronic hyperglycemia. If it is not managed properly, DM can lead to many severe complexities with time and can cause significant damage to the kidneys, heart, eyes, nerves and blood vessels. Diabetic foot ulcers (DFU) are one of those major complexities which affect around 15-25% of the population diagnosed with diabetes. Due to diabetic conditions, the body's natural healing process slows down leading to longer duration for healing of wounds only when taken care of properly. Herbal therapies are one of the approaches for the management and care of diabetic foot ulcer, which utilizes the concept of synergism for better treatment options. With the recent advancement in the field of nanotechnology and natural drug therapy, a lot of opportunities can be seen in combining both technologies and moving towards a more advanced drug delivery system to overcome the limitations of polyherbal formulations.

Methods: During the writing of this document, the data was derived from existing original research papers gathered from a variety of sources such as PubMed, ScienceDirect, Google Scholar.

Conclusion: Hence, this review includes evidence about the current practices and future possibilities of nano-herbal formulation in treatment and management of diabetic wounds.

Keywords: Diabetes Mellitus (DM); chronic wound; diabetic wound; nanotechnology; polyherbal nano formulation; wound healing.

Publication types

  • Review

MeSH terms

  • Diabetes Mellitus*
  • Diabetic Foot* / drug therapy
  • Drug Delivery Systems
  • Herbal Medicine
  • Humans
  • Hyperglycemia*
  • Phytotherapy