[Cardiac Protection Mechanism and Clinical Application of Dexmedetomidine]

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2022 Feb;44(1):130-135. doi: 10.3881/j.issn.1000-503X.12895.
[Article in Chinese]

Abstract

Dexmedetomidine is an α2 adrenoceptor agonist and has cardioprotective effect,the mechanism of which is being studied.Increasing studies have proved the clinical value of dexmedetomidine in reducing postoperative complications and improving the prognosis of patients.Therefore,this review summarizes the cardiac protection mechanism of dexmedetomidine based on the existing studies and expounds the application of dexmedetomidine in the perioperative period of cardiovascular surgery.

Keywords: cardiac protection; dexmedetomidine; perioperative period; surgery.

Publication types

  • Review

MeSH terms

  • Dexmedetomidine* / pharmacology
  • Dexmedetomidine* / therapeutic use
  • Heart
  • Humans

Substances

  • Dexmedetomidine