Phosphoproteomics profiling reveals a kinase network conferring acute myeloid leukaemia intrinsic chemoresistance and indicates HMGA1 phosphorylation as a potential influencer

Affiliations

• ¹ Department of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematologic Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope Medical Center, Duarte, California, USA.
• ² Department of Hematology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
• ³ Institute of Genetics, Zhejiang University, Hangzhou, China.
• ⁴ Department of Genetics, Zhejiang University School of Medicine, Hangzhou, China.
• ⁵ Department of Hematology, The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, Suzhou, China.
• ⁶ Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China.
• ⁷ Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.