Self-assembly of Peptide dendrimers and their bio-applications in theranostics

Mater Today Bio. 2022 Mar 8:14:100239. doi: 10.1016/j.mtbio.2022.100239. eCollection 2022 Mar.

Abstract

Nanotechnology has brought revolutionized advances in disease diagnosis and therapy. Self-assembled peptide dendrimers own novel physicochemical properties through the synergistic effects of the polypeptide chain, dendrimer and nano-structure, exhibiting great potential in theranostic. This review provides comprehensive insights into various peptide dendrimers for self-assembly. Their nanosize, morphology and composition are presented to understand self-assembly behaviors precisely. We further introduce the emerging theranostic applications based on specific imaging and efficient delivery recently.

Keywords: Cancer therapy; Diagnosis; Peptide dendrimer; Self-assembly.