Primary Amoebic Meningoencephalitis: Potential Application of Ionic Liquids Against Brain-Eating Amoebae?

Acta Parasitol. 2022 Jun;67(2):1032-1034. doi: 10.1007/s11686-022-00532-6. Epub 2022 Mar 16.

Abstract

Naegleria fowleri, a well-known brain-eating amoeba, induces high mortality with no available effective treatment. Ionic liquids are compounds that contain a variety of cations and anions that can be tailored to specific applications. Based on the biological, chemical and physical properties of these ionic liquids, this work proposes the use of ionic liquids as novel anti-Naegleria fowleri biocides.

Keywords: Brain-eating amoebae; Disinfection; Ionic liquids; Naegleria fowleri; Primary amoebic meningoencephalitis.

MeSH terms

  • Amebiasis*
  • Brain
  • Central Nervous System Protozoal Infections*
  • Humans
  • Ionic Liquids* / pharmacology
  • Naegleria fowleri*

Substances

  • Ionic Liquids