Restricted truncal sagittal movements of rapid eye movement behaviour disorder

Danielle Wasserman; Silvia Gullone; Iain Duncan; Mattia Veronese; Valentina Gnoni; Sean Higgins; Adam Birdseye; Emine Cigdem Gelegen; Peter J Goadsby; Keyoumars Ashkan; K Ray Chaudhuri; Giulio Tononi; Panagis Drakatos; Ivana Rosenzweig

doi:10.1038/s41531-022-00292-0

Restricted truncal sagittal movements of rapid eye movement behaviour disorder

NPJ Parkinsons Dis. 2022 Mar 15;8(1):26. doi: 10.1038/s41531-022-00292-0.

Authors

Danielle Wasserman^{1

2}, Silvia Gullone¹, Iain Duncan^{1

2}, Mattia Veronese^{1

3}, Valentina Gnoni^{1

2}, Sean Higgins^{1

2}, Adam Birdseye^{1

2}, Emine Cigdem Gelegen^{1

4}, Peter J Goadsby⁵, Keyoumars Ashkan⁶, K Ray Chaudhuri⁷, Giulio Tononi⁸, Panagis Drakatos^{2

9}, Ivana Rosenzweig^{10

11}

Affiliations

¹ Sleep and Brain Plasticity Centre, Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London (KCL), London, UK.
² Sleep Disorders Centre, St. Thomas' and Guy's Hospital, GSTT NHS, London, UK.
³ Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.
⁴ Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.
⁵ NIHR-Wellcome Trust King's Clinical Research Facility, King's College London, London, UK.
⁶ Department of Neurosurgery, King's College Hospital, London, UK.
⁷ King's College London and Parkinson's Foundation Centre of Excellence, King's College Hospital, London, UK.
⁸ Department of Psychiatry, University of Wisconsin-Madison, Madison, WI, USA.
⁹ Faculty of Life and Sciences Medicine, King's College London, London, UK.
¹⁰ Sleep and Brain Plasticity Centre, Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London (KCL), London, UK. ivana.1.rosenzweig@kcl.ac.uk.
¹¹ Sleep Disorders Centre, St. Thomas' and Guy's Hospital, GSTT NHS, London, UK. ivana.1.rosenzweig@kcl.ac.uk.

Abstract

Unlike sleep-walkers, patients with rapid-eye-movement-behaviour disorder (RBD) rarely leave the bed during the re-enactment of their dreams. RBD movements may be independent of spatial co-ordinates of the 'outside-world', and instead rely on (allocentric) brain-generated virtual space-maps, as evident by patients' limited truncal/axial movements. To confirm this, a semiology analysis of video-polysomnography records of 38 RBD patients was undertaken and paradoxically restricted truncal/thoraco-lumbar movements during complex dream re-enactments demonstrated.

Abstract

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