Objective: To observe the effect of thumb-tack needles based on "Biaoben acupoint compatibility" on sequela symptoms, mental state and pulmonary ventilation function in patients with coronavirus disease 2019 (COVID-19) during recovery period.
Methods: Fifty cases of COVID-19 during recovery period were randomly divided into an observation group and a control group, 25 cases in each group. The patients in the observation group were treated with thumb-tack needles at Guanyuan (CV 4), Zusanli (ST 36) and Taiyuan (LU 9). The patients in the control group were treated with sham thumb-tack needles at identical acupoints as the observation group. The treatment in the two groups was given once a day, 7-day treatment was taken as a course of treatment, and totally two courses of treatment were given. The TCM symptom score, Hamilton anxiety scale (HAMA) score, Hamilton depression scale (HAMD) score, pulmonary function (forced vital capacity [FVC], forced expiratory volume in the first second [FEV1], peak expiratory flow [PEF]), the severity of pulmonary ventilation dysfunction and pulmonary imaging changes in the two groups were compared before and after treatment.
Results: Compared before treatment, the total scores and each item scores of TCM symptom scale, HAMA scores and HAMD scores in the two groups were reduced after treatment (P<0.05). Except for the symptom scores of dry throat and dry stool, the total score and each item score of TCM symptom scale, HAMA score and HAMD score in the observation group were lower than those in the control group (P<0.05). Compared before treatment, FVC, FEV1 and PEF in the two groups were increased after treatment (P<0.05), and those in the observation group were higher than the control group (P<0.05). The severity of pulmonary ventilation dysfunction in the two groups was reduced after treatment (P<0.05), and the severity in the observation group was better than that in the control group (P<0.05). After treatment, the lung shadow area in the two groups was decreased (P<0.05), and that in the observation group was smaller than the control group (P<0.05). The improvement of imaging change in the observation group was better than that in the control group (P<0.05).
Conclusion: The thumb-tack needles based on "Biaoben acupoint compatibility" could significantly reduce the sequela symptoms, anxiety and depression in patients with COVID-19 during recovery stage, and improve the pulmonary ventilation function.
目的：观察“标本配穴”揿针对新型冠状病毒肺炎恢复期患者后遗症状、精神状态及肺通气功能的影响。方法：将50例新型冠状病毒肺炎恢复期患者随机分为观察组和对照组，各25例。观察组采用揿针治疗，穴取关元、足三里、太渊；对照组选用特制皮内针具进行假埋针处理，取穴同观察组。每天1次，7 d为一疗程，共治疗2个疗程。比较两组患者治疗前后中医症状评分、汉密尔顿焦虑量表（HAMA）评分、汉密尔顿抑郁量表（HAMD）评分、肺功能参数[用力肺活量（FVC）、第1秒用力呼气容积（FEV1）、潮气峰流量（PEF）]、肺通气功能障碍程度及肺部影像学变化。结果：治疗后，两组患者中医症状总分及各项评分、HAMA评分、HAMD评分均较治疗前降低（P<0.05）；除咽干和大便干结评分外，观察组患者中医症状总分及各项评分、HAMA评分、HAMD评分均低于对照组（P<0.05）。治疗后，两组患者FVC、FEV1、PEF均较治疗前升高（P<0.05），且观察组高于对照组（P<0.05）；两组患者肺通气功能障碍程度减轻（P<0.05），且观察组优于对照组（P<0.05）。治疗后，两组患者肺部阴影面积均缩小（P<0.05），且观察组小于对照组（P<0.05），观察组影像学变化改善优于对照组（P<0.05）。结论：“标本配穴”揿针治疗能明显减轻新型冠状病毒肺炎恢复期患者后遗症状以及焦虑抑郁精神症状，改善肺通气功能。.
Keywords: Biaoben acupoint compatibility; coronavirus disease 2019 (COVID-19); recovery stage; sequela; thumb-tack needles.