Long-term outcomes of pediatric infections: from traditional infectious diseases to long Covid

Future Microbiol. 2022 May:17:551-571. doi: 10.2217/fmb-2022-0031. Epub 2022 Mar 10.

Abstract

There is limited evidence available on the long-term impact of SARS-CoV-2 infection in children. In this article, the authors analyze the recent evidence on pediatric long Covid and lessons learnt from a pediatric post-Covid unit in Rome, Italy. To gain a better understanding of the concerns raised by parents and physicians in relation to the potential long-term consequences of this novel infection, it is important to recognize that long-term effect of a post-infectious disease is not a new phenomenon.

Keywords: COVID-19; SARS-CoV-2; children; long Covid; microclots; post-COVID-19 condition; viral persistence.

Plain language summary

The authors analyze the recent evidence on pediatric long Covid and lessons learnt from a pediatric post-Covid unit in Rome, Italy. Also, we analyze the long-term effects of other infectious diseases.

Publication types

  • Review

MeSH terms

  • COVID-19* / complications
  • Child
  • Communicable Diseases*
  • Humans
  • Italy / epidemiology
  • Post-Acute COVID-19 Syndrome
  • SARS-CoV-2