Small varices in chronic liver diseases

Curr Opin Gastroenterol. 2022 May 1;38(3):239-250. doi: 10.1097/MOG.0000000000000835. Epub 2022 Mar 7.

Abstract

Purpose of review: Gastroesophageal varices are common complications of chronic liver diseases (CLDs) and portal hypertension. Small varices have the risk of progressing to larger varices, causing bleeding or even death. Thus, early detection and appropriate management of small varices are necessary. The purpose of this review is to summarize the advance in the recent 5years about diagnosing and managing the small varices in CLDs.

Recent findings: The diagnosing methods of small varices in recent studies include improved endoscopic examinations, such as capsule endoscopy, and many noninvasive methods, including blood tests, ultrasound, computed tomography and magnetic resonance. For the management of small varices, though it is controversial, prevention using nonselective beta-blockers is still an essential part.

Summary: In this review, we summarize the classification of varices, the invasive and noninvasive diagnostic methods, their performances, and the emerging progression in the management of small varices in the recent 5 years. We hope that this review provides relevant information to understand better and appropriately manage small varices.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Capsule Endoscopy* / methods
  • Esophageal and Gastric Varices* / complications
  • Esophageal and Gastric Varices* / etiology
  • Gastrointestinal Hemorrhage / diagnosis
  • Gastrointestinal Hemorrhage / etiology
  • Gastrointestinal Hemorrhage / therapy
  • Hemorrhage
  • Humans
  • Hypertension, Portal* / complications
  • Hypertension, Portal* / diagnosis
  • Liver Cirrhosis / complications
  • Varicose Veins* / complications
  • Varicose Veins* / diagnosis