Fluorine-18-fluorodeoxyglucose-positron emission tomography/computed tomography (18F-FDG PET/CT) plays an important role in the management of thyroid malignancies. Incidentally found FDG avid nodule needs further workup to rule out its malignant potential. 18F-FDG PET/CT has a proven role in detecting recurrent disease or the metastatic workup of the thyroglobulin elevated negative radioiodine scan (TENIS) scenario. In managing histologically aggressive carcinoma of the thyroid, 18F-FDG PET/CT has a proven role. The theranostic potential has been explored with PET/CT using 68Ga-SSA, 68Ga-PSMA,68Ga-FAPI, and 68Ga-DOTA-RGD. The 124I PET/CT role is just being investigated for better spatial resolution and helps in dosimetry.
Keywords: 18F-FDG PET/CT; Differentiated thyroid cancer; Medullary thyroid cancer; TENIS; Thyroid cancer.
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