Recent developments and trends of automatic nucleic acid detection systems

Xujun Yuan; Guodong Sui; Dawei Zhang; Min Chen; Wang Zhao

doi:10.1016/j.jobb.2022.02.001

Recent developments and trends of automatic nucleic acid detection systems

J Biosaf Biosecur. 2022 Jun;4(1):54-58. doi: 10.1016/j.jobb.2022.02.001. Epub 2022 Feb 28.

Authors

Xujun Yuan^{1

2}, Guodong Sui^{1

3}, Dawei Zhang^{1

4}, Min Chen⁵, Wang Zhao^{1

3}

Affiliations

¹ Shanghai Environmental Biosafety Instruments and Equipment Engineering Technology Research Center, University of Shanghai for Science and Technology, 516 Jungong Road, Shanghai 200093, PR China.
² Shanghai Cohere Electronic Technology Company, No. 10 Building, 2888 Shengang Road, Shanghai 201101, PR China.
³ Shanghai Key Laboratory of Atmospheric Particle Pollution Prevention (LAP3), Department of Environmental Science & Engineering, Fudan University, 2005 Songhu Road, Shanghai 200438, PR China.
⁴ Engineering Research Center of Optical Instrument and System, the Ministry of Education, Shanghai Key Laboratory of Modern Optical System, University of Shanghai for Science and Technology, 516 Jungong Road, Shanghai 200093, PR China.
⁵ Shanghai Municipal Center for Disease Control & Prevention, 1380 West Zhongshan Road, Shanghai 200336, PR China.

Abstract

Nucleic acid detection, widely used in clinical diagnosis, biological analysis, and environmental monitoring, is of great significance for disease diagnosis and basic research. With the outbreak of COVID-19, the demand for fast and high-throughput nucleic acid detection from large numbers of samples has increased sharply. Automated nucleic acid detection systems can meet these needs, and also play important roles in disease screening and infectious disease prevention and control. In this review, we introduce and compare the current mainstream nucleic acid automatic detection instruments and equipment, then discuss the future demands of nucleic acid detection.

Keywords: Automatic systems; Nucleic acid detection.

Publication types

Review