Background: Type II Diabetes mellitus (T2DM) patients are at the risk of developing cerebrovascular diseases, often contributed by altered cerebral haemodynamics. We present a systematic review of studies on cerebral haemodynamics assessment using transcranial Doppler (TCD) in T2DM.
Review method: A systematic review of the published articles in the English language between 1991 to 2021.
Data sources: Articles were retrieved via Pubmed and Cochrane library. We included Cross-sectional, prospective, retrospective, randomized controlled, and cross-over studies for this review.
Results: A total of 25 articles met the inclusion criteria, which provided data for 3212 patients.
Conclusion: Cerebral autoregulation is often impaired among patients with T2DM. The risk increased with the duration of T2DM, related complications and presence of comorbidities.
Keywords: Cerebral haemodynamics; Cerebrovascular reactivity; Transcranial Doppler; Type II diabetes mellitus.
Copyright © 2022. Published by Elsevier B.V.