FcεRI- and MRGPRX2-evoked acute degranulation responses are fully additive in human skin mast cells

Magda Babina; Zhao Wang; Zhuoran Li; Kristin Franke; Sven Guhl; Metin Artuc; Torsten Zuberbier

doi:10.1111/all.15270

FcεRI- and MRGPRX2-evoked acute degranulation responses are fully additive in human skin mast cells

Allergy. 2022 Jun;77(6):1906-1909. doi: 10.1111/all.15270. Epub 2022 Mar 11.

Authors

Magda Babina^{1

2

3}, Zhao Wang^{1

2

4}, Zhuoran Li^{1

2

3}, Kristin Franke^{1

2

3}, Sven Guhl^{1

2

3}, Metin Artuc^{1

2

3}, Torsten Zuberbier^{1

2

3}

Affiliations

¹ Institute for Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
² Berlin Institute of Health, Berlin, Germany.
³ Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin, Germany.
⁴ Department of Dermatology, The Second Affiliated Hospital, Northwest Hospital, Xi'an Jiaotong University, Xi'an, China.

PMID: 35246987
DOI: 10.1111/all.15270

No abstract available

Keywords: FcεRI; MRGPRX2; anaphylaxis; drug allergy; mast cell.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Cell Degranulation
Humans
Mast Cells* / physiology
Nerve Tissue Proteins / genetics
Receptors, G-Protein-Coupled
Receptors, IgE*
Receptors, Neuropeptide / genetics
Skin

Substances

MRGPRX2 protein, human
Nerve Tissue Proteins
Receptors, G-Protein-Coupled
Receptors, IgE
Receptors, Neuropeptide