Research Progress of Zebrafish Model in Toxicology and Its Application Prospects in Forensic Science

Fa Yi Xue Za Zhi. 2021 Dec 25;37(6):867-872. doi: 10.12116/j.issn.1004-5619.2021.310902.
[Article in English, Chinese]

Abstract

In recent years, zebrafish model has been widely concerned and recognized by scholars at home and abroad. As an animal model, zebrafish is of great research value because it is easy to feed, easy to operate, observe and analyze, and the model results can be highly combined with human body test data. Zebrafish model has been widely used in many fields, including basic medical science, clinical medicine, agricultural production, environmental toxicology and forensic science. This review introduces the biological characteristics of zebrafish, summarizes the research progress of zebrafish model in toxicology, and discusses the application prospect of zebrafish model in forensic science.

近年来,斑马鱼模型获得了国内外学者的广泛关注和认可。作为一种动物模型,斑马鱼因其易于饲养、便于操作和观察分析、模型研究结果与人体检测数据的可融合性高等特点而具有很大的研究价值,被应用于基础医学、临床医学、农业生产、生态毒理、司法鉴定等诸多领域。本文从斑马鱼的生物学特性出发,总结斑马鱼模型的毒理学研究进展,展望其在司法鉴定中的应用前景。.

Keywords: animal model; drug abuse; environmental pollution; forensic toxicology; review; zebrafish.

Publication types

  • Review

MeSH terms

  • Animals
  • Forensic Sciences*
  • Forensic Toxicology
  • Humans
  • Zebrafish*