Drug problem is a major social and public security problem in the world. Drug abuse poses a great threat to economic development, social stability and public health. In recent years, synthetic drugs represented by methamphetamine have surpassed traditional drugs such as morphine, heroin, ketamine and become one of the most abused drugs in the world. In order to solve the problem of drug abuse, it is of great theoretical value and practical significance to carry out all-round and multi-level scientific research on drug-related issues. Based on the current situation of drug abuse, this article reviews research progresses on the epidemiology of methamphetamine abuse, the monitoring technology, the basic researches on toxicity damage, the withdrawal drug screening, the related clinical comorbidity and the testing technologies, comprehensively presenting the development trend of methamphetamine abuse related issues.
毒品问题是世界性的重大社会公共安全问题，毒品滥用给经济发展、社会稳定和人民健康带来巨大威胁。近年来，以甲基苯丙胺为代表的合成毒品滥用已超过吗啡、海洛因、氯胺酮等传统毒品，成为世界范围内滥用最多的毒品之一。为解决毒品滥用这一重大社会公共安全问题，开展全方位、多层次的毒品相关问题的科学研究具有重要的理论价值和实践意义。本文立足当前毒品滥用形势，对合成毒品甲基苯丙胺滥用的流行病学特征、监测技术、毒性损害基础研究、戒断药物筛选、相关的临床共病以及检测技术等方面的研究进展进行综述，全面展现甲基苯丙胺滥用相关问题的发展趋势。.
Keywords: addiction; comorbidity; forensic toxicology; methamphetamine; review; substance abuse.