Teach 'em young: Influenza vaccines induce broadly neutralizing antibodies in children

Haley L Dugan; Patrick C Wilson

doi:10.1016/j.xcrm.2022.100531

Teach 'em young: Influenza vaccines induce broadly neutralizing antibodies in children

Cell Rep Med. 2022 Feb 15;3(2):100531. doi: 10.1016/j.xcrm.2022.100531.

Authors

Haley L Dugan¹, Patrick C Wilson²

Affiliations

¹ Adimab, LLC, Lebanon, NH 03766, USA.
² Department of Pediatrics, Weill Cornell Medical College, NY 10065, USA.

Abstract

Antibodies against the influenza virus hemagglutinin stalk afford broad protection against antigenically drifted viruses. In this issue of Cell Reports Medicine, Yegorov et al.¹ identify that current vaccine formulations induce neutralizing stalk antibodies in children-a highly vulnerable population.

Publication types

News
Comment

MeSH terms

Antibodies, Neutralizing / immunology
Antibodies, Viral / immunology
Broadly Neutralizing Antibodies
Child
Hemagglutinin Glycoproteins, Influenza Virus / immunology
Humans
Influenza Vaccines* / therapeutic use
Influenza, Human* / prevention & control
Seasons
Vaccines, Attenuated

Substances

Antibodies, Neutralizing
Antibodies, Viral
Broadly Neutralizing Antibodies
Hemagglutinin Glycoproteins, Influenza Virus
Influenza Vaccines
Vaccines, Attenuated