From mating to mama bear: Distinct VMHvl cell types drive female reproductive state-dependent behavior

Shuyu Wang; Kimberly L P Long; Devanand S Manoli

doi:10.1016/j.neuron.2022.02.007

From mating to mama bear: Distinct VMHvl cell types drive female reproductive state-dependent behavior

Neuron. 2022 Mar 2;110(5):737-739. doi: 10.1016/j.neuron.2022.02.007.

Authors

Shuyu Wang¹, Kimberly L P Long¹, Devanand S Manoli²

Affiliations

¹ Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA 95158, USA; Center for Integrative Neuroscience, University of California, San Francisco, San Francisco, CA 95158, USA; Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 95158, USA; Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA 95158, USA.
² Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA 95158, USA; Center for Integrative Neuroscience, University of California, San Francisco, San Francisco, CA 95158, USA; Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 95158, USA; Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA 95158, USA. Electronic address: devanand.manoli@ucsf.edu.

PMID: 35240060
DOI: 10.1016/j.neuron.2022.02.007

Abstract

In this issue of Neuron, Liu et al. (2022) molecularly identify subsets of estrogen receptor-1-positive neurons within the female ventrolateral subdivision of the ventromedial hypothalamus activated during sexual receptivity versus agonistic behaviors in distinct reproductive states and demonstrate that these subsets control state-dependent changes in social behaviors.

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MeSH terms

Animals
Female
Hypothalamus / physiology
Neurons / physiology
Sexual Behavior, Animal* / physiology
Social Behavior