Neuropsychiatric systemic lupus erythematosus in a girl with neurocutaneous melanosis caused by a somatic mutation in NRAS

Rheumatology (Oxford). 2022 Aug 3;61(8):e224-e226. doi: 10.1093/rheumatology/keac130.

Authors

Tomohiro Inoguchi¹, Toshiki Takenouchi¹, Fumito Yamazaki¹, Yasushi Kondo², Hiroto Mitamura³, Kenjiro Kosaki⁴, Takao Takahashi¹

Affiliations

¹ Department of Pediatrics.
² Division of Rheumatology, Department of Internal Medicine.
³ Department of Ophthalmology.
⁴ Center for Medical Genetics, Keio University School of Medicine, Tokyo, Japan.

PMID: 35238342
DOI: 10.1093/rheumatology/keac130

No abstract available

MeSH terms

Female
GTP Phosphohydrolases / genetics
Humans
Lupus Erythematosus, Systemic* / complications
Lupus Erythematosus, Systemic* / genetics
Lupus Vasculitis, Central Nervous System*
Magnetic Resonance Imaging
Melanosis* / genetics
Membrane Proteins / genetics
Mutation
Neurocutaneous Syndromes* / genetics

Substances

Membrane Proteins
GTP Phosphohydrolases
NRAS protein, human

Supplementary concepts

Neurocutaneous melanosis