Positron Emission Tomography in Atherosclerosis Research

Anne Roivainen; Mia Ståhle; Antti Saraste

doi:10.1007/978-1-0716-1924-7_50

Positron Emission Tomography in Atherosclerosis Research

Methods Mol Biol. 2022:2419:825-839. doi: 10.1007/978-1-0716-1924-7_50.

Authors

Anne Roivainen^{1

2}, Mia Ståhle³, Antti Saraste^{3

4}

Affiliations

¹ Turku PET Centre, University of Turku and Turku University Hospital, Turku, Finland. anne.roivainen@utu.fi.
² Turku Center for Disease Modeling, University of Turku, Turku, Finland. anne.roivainen@utu.fi.
³ Turku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.
⁴ Heart Center, Turku University Hospital and University of Turku, Turku, Finland.

PMID: 35238004
DOI: 10.1007/978-1-0716-1924-7_50

Abstract

Positron emission tomography (PET) is a quantitative imaging technique that uses molecules labeled with positron-emitting radionuclides to visualize and measure biochemical processes in the tissues of living subjects. In recent years, different PET tracers have been evaluated for their ability to characterize the atherosclerotic process in order to study the activity of the disease. Here, we describe detailed PET methods for preclinical studies of atherosclerosis and summarize the key methodological aspects of PET imaging in clinical studies of atherosclerosis.

Keywords: 18F-FDG; Autoradiography; In vivo positron emission tomography/computed tomography.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Atherosclerosis* / diagnostic imaging
Fluorodeoxyglucose F18
Humans
Positron-Emission Tomography / methods
Radioisotopes / chemistry
Radiopharmaceuticals*

Substances

Radioisotopes
Radiopharmaceuticals
Fluorodeoxyglucose F18