The landscape of transcriptomic and proteomic studies in sarcoidosis

Maneesh Bhargava; Shu-Yi Liao; Elliott D Crouser; Lisa A Maier; Sonia M Leach

doi:10.1183/23120541.00621-2021

The landscape of transcriptomic and proteomic studies in sarcoidosis

ERJ Open Res. 2022 Feb 28;8(1):00621-2021. doi: 10.1183/23120541.00621-2021. eCollection 2022 Jan.

Authors

Maneesh Bhargava^{1

2}, Shu-Yi Liao^{3

4

5

2}, Elliott D Crouser⁶, Lisa A Maier^{3

4

5}, Sonia M Leach⁷

Affiliations

¹ Division of Pulmonary, Critical Care and Sleep Medicine, Dept of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
² These authors contributed equally.
³ Division of Environmental and Occupational Health Sciences, Dept of Medicine, National Jewish Health, Denver, CO, USA.
⁴ Division of Pulmonary Sciences and Critical Care Medicine, Dept of Medicine, University of Colorado Denver, Aurora, CO, USA.
⁵ Dept of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado Denver, Aurora, CO, USA.
⁶ Division of Pulmonary and Critical Care Medicine, The Ohio State University, Columbus, OH, USA.
⁷ Center for Genes, Environment and Health, National Jewish Health, Denver, CO, USA.

Abstract

Multiple overlapping pathways are identified in tissue, BAL cells, PBMCs and a sarcoidosis in vitro granuloma model. Inferences from omic studies are constrained by small sample sizes. Studies comparing differences between sarcoidosis phenotypes are needed. https://bit.ly/30NaHz4.

Abstract

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