Isolation and characterization of a novel linear-plasmid phage from the sediment of the Mariana Trench

Virol Sin. 2022 Apr;37(2):311-313. doi: 10.1016/j.virs.2022.01.022. Epub 2022 Jan 28.

¹ State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
² Key Laboratory of Marine Genetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, Xiamen, 361005, China.
³ Shanghai Key Laboratory of Veterinary Biotechnology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, 200240, China.
⁴ State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, 519082, China.
⁵ State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, 519082, China. Electronic address: jiandy@sjtu.edu.cn.

Abstract

•
HMP1 is the first bacteriophage isolated from hadal sediment, with the highest water depth on record up to now.
•
The isolation of HMP1 extends the habitat of linear plasmid phages from the surface to the deep ocean.
•
The genomic and morphological features of HMP1 provide hints on the vertical exchange of viral communities in the ocean.
•
HMP1 and Halomonas sp. MT08-1 contribute a useful hadal phage-host system for in-depth analysis in the future.