Mixed neuroendocrine-non-neuroendocrine neoplasms of the right colon: a case report

Pan Afr Med J. 2021 Dec 21:40:243. doi: 10.11604/pamj.2021.40.243.30627. eCollection 2021.

Abstract

Mixed neuroendocrine-non neuroendocrine neoplasm (MiNENs) is a rare gastrointestinal neoplasm that has been redefined by the World Health Organization (WHO) in 2017 as the association of two types of components, neuroendocrine and non-neuroendocrine, each of them present in at least 30% of the tumour mass. Small case reports and case series have demonstrated the occurrence of this neoplasm in the colon. We here report the case of a 47-year-old man undergoing colonscopy for anemia. This showed impassable polypoidal tumor budding in the right colic flexure. Computerized tomography (CT) scan and magnetic resonance imaging (MRI) showed the presence of liver metastases. As the tumor was hemorrhagic, right hemicolectomy with lymph node dissection was performed. The histological examination showed MiNEN of the ascending colon. The patient received adjuvant chemotherapy.

Keywords: Ascending colon; adenocarcinoma; case report; neuroendocrine tumor G3.

Publication types

  • Case Reports

MeSH terms

  • Colon / pathology
  • Colonic Neoplasms* / diagnosis
  • Gastrointestinal Neoplasms*
  • Humans
  • Lymph Node Excision
  • Male
  • Middle Aged
  • Neuroendocrine Tumors* / diagnosis
  • Neuroendocrine Tumors* / pathology