[Efficacy of the Extract from Fermentation of Soybean and Rice Bran on Hyperglycemia]

Yakugaku Zasshi. 2022;142(3):289-293. doi: 10.1248/yakushi.21-00189.
[Article in Japanese]

Abstract

In recent years, lifestyle-related diseases such as hypertension and diabetes have been on the rise. These conditions can cause serious conditions such as myocardial and cerebral infarctions. Therefore, proper control of blood pressure and blood glucose levels is important issues in preventive medicine. Traditional fermented foods have been shown to have various functions, and their effects on lifestyle-related diseases have attracted particular attention. In this study, we investigated the effects of fermented soybeans and rice bran (OE-1) and supplements containing OE-1 on blood glucose levels and weight changes. We identified an inhibitory effect on elevated blood glucose levels upon administration of OE-1, and this effect was thought to be due to digestive enzyme inhibition. These effects of foods containing OE-1 are expected to have a positive effect on the prevention and improvement of lifestyle-related diseases as health foods.

Keywords: blood glucose level; body weight; fermented soybean extract; lifestyle-related disease.

MeSH terms

  • Adult
  • Animals
  • Blood Glucose / metabolism*
  • Body Weight / drug effects*
  • Diabetes Mellitus / etiology
  • Diabetes Mellitus / prevention & control*
  • Dietary Supplements*
  • Fermentation*
  • Glycine max / chemistry*
  • Humans
  • Hypertension / etiology
  • Hypertension / prevention & control*
  • Life Style
  • Male
  • Mice
  • Mice, Inbred ICR
  • Middle Aged
  • Oryza / chemistry*
  • Plant Extracts / administration & dosage
  • Plant Extracts / pharmacology*

Substances

  • Blood Glucose
  • Plant Extracts