Optical Coherence Tomography Findings in Infectious Posterior Uveitis

Ocul Immunol Inflamm. 2022 Apr 3;30(3):652-663. doi: 10.1080/09273948.2022.2032197. Epub 2022 Feb 28.

Abstract

Purpose: To describe and illustrate the main optical coherence tomography (OCT) findings of infectious uveitis.

Methods: Narrative review.

Results: Posterior segment OCT in patients with infectious uveitis reveals posterior hyaloid face precipitates, superficial retinal precipitates and infiltrates, foveolitis, retinitis, neuro-retinitis, choroidal granulomas, and choroiditis as main imaging biomarkers. Some of these features are specific to the underlying causing etiology and may support the diagnosis and the initiation of treatment. Some OCT features disappear completely with resolution; some others are associated with irreversible retinal damage.

Conclusions: OCT identifies different features of infectious uveitis into the vitreous, the retina, and the choroid. OCT characteristics, combined with other multimodal imaging features, are helpful in the differential diagnosis of infectious uveitis, the early detection of complications, and the assessment of the response to therapy.

Keywords: Optical coherence tomography; biomarkers; infectious uveitis.

Publication types

  • Review

MeSH terms

  • Choroid
  • Eye Infections* / complications
  • Fluorescein Angiography / methods
  • Humans
  • Retinitis* / etiology
  • Tomography, Optical Coherence / methods
  • Uveitis* / complications
  • Uveitis* / diagnosis
  • Uveitis, Posterior* / complications
  • Uveitis, Posterior* / diagnosis