Psychosocial Treatments for Bipolar Disorder in Children and Adolescents

Annu Rev Clin Psychol. 2022 May 9:18:291-327. doi: 10.1146/annurev-clinpsy-072220-021237. Epub 2022 Feb 25.

Abstract

Evidence suggests that adjunctive psychosocial intervention for the treatment of pediatric bipolar spectrum disorders (BPSDs) is effective, feasible, and highly accepted as both an acute and maintenance treatment for youth with BPSD diagnoses as well as a preventive treatment for high-risk youth who are either asymptomatic or exhibit subsyndromal mood symptoms. Here, we provide a comprehensive review of all known evidence-based interventions, including detailed descriptions of treatment targets and core components, results of clinical trials, and updated research on mediators and moderators of treatment efficacy. Treatments are presented systematically according to level of empirical support (i.e., well established, probably efficacious, possibly efficacious, experimental, or questionable); upcoming and ongoing trials are included when possible. In line with a staging approach, preventive interventions are presented separately. Recommendations for best practices based on age, stage, and additional evidence-based child and family factors shown to affect treatment outcomes are provided.

Keywords: adolescent; bipolar disorder; child; manic depression; psychotherapy; youth.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Bipolar Disorder* / therapy
  • Child
  • Humans
  • Treatment Outcome