Colorectal cancer (CRC) represents one of the most frequent human cancer entities and is still amongst the "top killers" in human cancer, although fundamental progress has been made in recent years in CRC prevention, early diagnosis, basic and translational research, and (targeted) therapy [...].
Keywords: (molecular) carcinogenesis; (single) cancer cell heterogeneity; (targeted) therapy; cancer progression; colorectal cancer; infectious agents; metastasis; models; personalized medicine.