Research Progress of Graphene and Its Derivatives towards Exhaled Breath Analysis

Biosensors (Basel). 2022 Jan 18;12(2):48. doi: 10.3390/bios12020048.

Abstract

The metabolic process of the human body produces a large number of gaseous biomarkers. The tracking and monitoring of certain diseases can be achieved through the detection of these markers. Due to the superior specific surface area, large functional groups, good optical transparency, conductivity and interlayer spacing, graphene, and its derivatives are widely used in gas sensing. Herein, the development of graphene and its derivatives in gas-phase biomarker detection was reviewed in terms of the detection principle and the latest detection methods and applications in several common gases, etc. Finally, we summarized the commonly used materials, preparation methods, response mechanisms for NO, NH3, H2S, and volatile organic gas VOCs, and other gas detection, and proposed the challenges and prospective applications in this field.

Keywords: biomarkers; charge transfer; colorimetry; gas sensing; graphene.

Publication types

  • Review

MeSH terms

  • Ammonia / analysis
  • Biomarkers / analysis
  • Breath Tests / methods
  • Exhalation
  • Graphite*
  • Humans
  • Nitric Oxide / analysis
  • Sulfuric Acids / analysis
  • Volatile Organic Compounds* / analysis

Substances

  • Biomarkers
  • Sulfuric Acids
  • Volatile Organic Compounds
  • Nitric Oxide
  • Ammonia
  • Graphite
  • sulfuric acid