Multisystem Inflammatory Syndrome in Children Unmasking Brugada Type 1 Pattern

Carla G Corti; Alessandro Seganti; Antonio Sanzo; Luisa F Nespoli; Sara Goletto; Francesca Izzo; Gian Vincenzo Zuccotti; Savina Mannarino

doi:10.1016/j.jaccas.2021.12.023

Multisystem Inflammatory Syndrome in Children Unmasking Brugada Type 1 Pattern

JACC Case Rep. 2022 Feb 16;4(4):205-210. doi: 10.1016/j.jaccas.2021.12.023.

Authors

Carla G Corti¹, Alessandro Seganti², Antonio Sanzo², Luisa F Nespoli¹, Sara Goletto¹, Francesca Izzo³, Gian Vincenzo Zuccotti⁴, Savina Mannarino¹

Affiliations

¹ Pediatric Cardiology, Department of Pediatrics, Children's Hospital Vittore Buzzi, Milan, Italy.
² Coronary Care Unit and Laboratory of Clinical and Experimental Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
³ Division of Pediatric Anesthesia and Intensive Care Unit, Department of Pediatrics, Children's Hospital Vittore Buzzi, Milan, Italy.
⁴ Department of Biomedical and Clinical Science "L. Sacco," University of Milan, Milan, Italy.

Abstract

We describe the case of a 14-year-old boy hospitalized for multisystem inflammatory syndrome in children who developed atrial fibrillation during the acute phase and a transient Brugada type 1 pattern in the subacute phase. Eight months later, a provocative test with ajmaline confirmed the suspicion of Brugada syndrome. (Level of Difficulty: Intermediate.).

Keywords: BP, Brugada phenocopy; BrS, Brugada syndrome; Brugada phenocopy; Brugada syndrome; ECG, electrocardiographic; MIS-C, multisystem inflammatory syndrome in children; MPL, modified precordial lead; SARS-CoV-2, severe acute respiratory syndrome-coronavirus-2; autonomic system dysregulation; cytokine storm; multisystem inflammatory syndrome in children.

Publication types

Case Reports