Cellular reprogramming and the rise of rejuvenation biotech

João Pedro de Magalhães; Alejandro Ocampo

doi:10.1016/j.tibtech.2022.01.011

Cellular reprogramming and the rise of rejuvenation biotech

Trends Biotechnol. 2022 Jun;40(6):639-642. doi: 10.1016/j.tibtech.2022.01.011. Epub 2022 Feb 18.

Authors

João Pedro de Magalhães¹, Alejandro Ocampo²

Affiliations

¹ Integrative Genomics of Ageing Group, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK. Electronic address: jp@senescence.info.
² Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland.

PMID: 35190201
DOI: 10.1016/j.tibtech.2022.01.011

Abstract

Cells can be rejuvenated and biological clocks reset using cellular reprogramming. A growing number of companies now aim to use cellular reprogramming to develop therapies for rejuvenating human beings. Can the 'young' science of rejuvenation, currently mostly based on in vitro studies, drive a new biotech field toward clinical applications?

Keywords: Yamanaka factors; aging; gene therapy; longevity.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biotechnology
Cellular Reprogramming*
Humans
Rejuvenation*
Research Design

Abstract

Publication types

MeSH terms

Grants and funding