Characterisation of two unique sesquiterpenoids from Trichoderma hypoxylon

Jinyu Zhang; Wen-Bing Yin

doi:10.1080/21501203.2021.1964630

Characterisation of two unique sesquiterpenoids from Trichoderma hypoxylon

Mycology. 2021 Aug 12;13(1):32-38. doi: 10.1080/21501203.2021.1964630. eCollection 2022.

Authors

Jinyu Zhang^{1

2}, Wen-Bing Yin^{1

2}

Affiliations

¹ State Key Laboratory Of Mycology, Institute Of Microbiology, Chinese Academy Of Sciences, Beijing, Republic of China.
² University Of Chinese Academy Of Sciences, Beijing, Republic of China.

Abstract

Two new sesquiterpenoids, 1-2, together with three known compounds, were isolated from Trichoderma hypoxylon. Among the known compounds, compound 4 was isolated as naturally occurring compound for the first time. The structures of these new compounds were characterized by HR-ESI-MS and spectroscopic methods including 1D and 2D NMR. The absolute configurations of 1-2 were assigned by electronic circular dichroism (ECD) calculations.

Keywords: Sesquiterpenes; fungi; glycoside; rearranged cuparane; trichoderma.

Grants and funding

This work was supported by the National Key Research and Development Program of China (2018YFA0901901); and National Natural Science Foundation of China (21778075), and Construction of the Registry and Database of Bioparts for Synthetic Biology, CAS (ZSYS-016)